Bioprocess Monitoring and Control

This is the first comprehensive volume on bioprocess automation and control. It addresses bioprocess engineers and biotechnologists seeking information about new devices and advanced control techniques, including those who are not be specialists in process control. It also offers guidance for control engineers who are used to classical problems in mechanical, electrical, or chemical engineering but who may not be familiar with the specifics of nonlinear, time-dependent bioprocesses and the instrumentation required to ... Read More

This is the first comprehensive volume on bioprocess automation and control. It addresses bioprocess engineers and biotechnologists seeking information about new devices and advanced control techniques, including those who are not be specialists in process control. It also offers guidance for control engineers who are used to classical problems in mechanical, electrical, or chemical engineering but who may not be familiar with the specifics of nonlinear, time-dependent bioprocesses and the instrumentation required to monitor them. The book begins with the development and analysis of control structures and describes available biosensors. Underlying soft sensor estimation techniques are outlined along with methods for using derived information. The coverage of industrial applications treats both low-level control loops (temperature, pH, etc.) and high-level control strategies (setpoint optimization, optimal trajectories, adaptive control, etc.). The international team of authors detail each topic in a thorough and complete manner, and provide an important source of information for both experienced users and those new to computer controlled fermentation systems. The intended readership includes chemical, control and bioprocess engineers; biochemists and biologists; and graduate students in biotechnology. Read Less