Introduction: Discovery of Nitric Oxide (NO). Sect.I: Chemistry.-1. The Chemical Biology of NO. Balancing NO with Oxidative and Nitrosative Stress.- Sect.II: Biochemistry and Pharmacology of NO, Synthesis and Action.-2. Enzymology of NO Synthases.- 3. Regulation of NO Synthase Expression and Activity.- 4. Enzymology of Soluble Guanylyl Cyclase.- 5. NO Synthase Inhibitors I: Substrate Analogs and Heme Ligands.- 6. NO Synthase Inhibitors II: Pterin Antagonists/ Anti-Pterins.- 7. Mechanisms of Cellular Resistance Against NO.- ...
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Introduction: Discovery of Nitric Oxide (NO). Sect.I: Chemistry.-1. The Chemical Biology of NO. Balancing NO with Oxidative and Nitrosative Stress.- Sect.II: Biochemistry and Pharmacology of NO, Synthesis and Action.-2. Enzymology of NO Synthases.- 3. Regulation of NO Synthase Expression and Activity.- 4. Enzymology of Soluble Guanylyl Cyclase.- 5. NO Synthase Inhibitors I: Substrate Analogs and Heme Ligands.- 6. NO Synthase Inhibitors II: Pterin Antagonists/ Anti-Pterins.- 7. Mechanisms of Cellular Resistance Against NO.- Sect. III: Physiological Functions of NO.- 8. NO and Regulation of Vascular Tone.- 9. Regulation of Cardiac Function by NO.- 10. Regulation of Platelet Function.- 11. The Physiological Role of NO in the Central Nervous System. 12. The Role of NO in the Peripheral Nervous System. 13. NO and Neuroendocrine Function.- 14. The Role of NO in Kidney Function. Section IV: The Role of Pharmacological Action of NO in Human Disease.- 15. Therapeutic Importance of Nitrovasodilators.- 16. Therapeutic Potential of NOS Inhibitors in Septic Shock.- 17. Inhalation Therapy with NO Gas.- 18. The Function of NO in the Immune System.- 19. NO: A True Inflammatory Mediator.- 20. NO in the Immunopathogenesis of Type-1 Diabetes.- 21. The Role of NO in Cardiac Ischemia--Reperfusion, - 22. NO and Atherosclerosis.- 23. NO in Brain Ischemia/Reperfusion Injury.- 24. Therapeutic Potential of NO Synthase Gene Manipulation.
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Very Good. First Edition, First Printing. Published by Springer, 2000. Octavo. Hardcover. Book is very good with bookplate on flyleaf and slight spine lean. No dust jacket as issued. An excellent copy of this comprehensive science work on Nitric Oxide.100% positive feedback. 30 day money back guarantee. NEXT DAY SHIPPING! Excellent customer service. Please email with any questions. All books packed carefully and ship with free delivery confirmation/tracking. All books come with free bookmarks. Ships from Sag Harbor, New York.